When do you get to that point of enough is enough?

Quote from The Mexican (2001 film)
http://m.imdb.com/title/tt0236493/quotes

Samantha: I have to ask you a question. It's a good one so think about it. If two people love each other, but they just can't seem to get it together, when do you get to that point of enough is enough?
Jerry: Never.